Effects of Acridine Derivatives on Ca2+ Uptake by Candida albicans
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چکیده
منابع مشابه
INHIBITION OF14C UPTAKE BY CANDIDA ALBICANS: A NEW METHOD FOR INVESTIGATION OF INTRACELLULAR KILLING BY PHAGOCYTES
A radio assay employing 14C-uridine to measure the intracellular killing of Candida albicans by phagocytes is presented. The principle of this new method is that after killing of Candida albicans by phagocytes RNA synthesis stops and therefore uridine uptake is diminished whilst viable candida in cultures would take up uridine and as a result, high CPM counts can be obtained within 135 min...
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OBJECT To determine if tetracycline, previously reported to increase the probability of developing symptomatic vaginal yeast infections, has a direct effect on Candida albicans growth or induction of virulent phenotypes. METHOD In vitro, clinical isolates of yeast were cultivated with sublethal concentrations of tetracycline and yeast cell counts, hyphal formation, drug efflux pump activity, ...
متن کاملCalcification by Candida albicans.
Candida albicans was grown in a chamically defined medium in which certain microorganisms are known to calcify. The fungus developed calcium phosphate deposits with the same X-ray diffraction maxima as biological apatite.
متن کاملinhibition of14c uptake by candida albicans: a new method for investigation of intracellular killing by phagocytes
a radio assay employing 14c-uridine to measure the intracellular killing of candida albicans by phagocytes is presented. the principle of this new method is that after killing of candida albicans by phagocytes rna synthesis stops and therefore uridine uptake is diminished whilst viable candida in cultures would take up uridine and as a result, high cpm counts can be obtained within 135 min. of ...
متن کاملUptake of T-2307, a novel arylamidine, in Candida albicans.
OBJECTIVES T-2307, a novel arylamidine synthesized at Toyama Chemical Co., Ltd, has in vitro and in vivo broad-spectrum activities against pathogenic fungi. T-2307 particularly exhibits potent in vitro and in vivo activity against Candida albicans, suggesting that its uptake might be mediated by a transport system. In this report, we studied the uptake of T-2307 in C. albicans. METHODS C. alb...
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ژورنال
عنوان ژورنال: Bioenergetics: Open Access
سال: 2017
ISSN: 2167-7662
DOI: 10.4172/2167-7662.1000152